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Featured Clinical Trials Supported by the National Cancer Institute
Today, hundreds of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials featured in the NCI Cancer Bulletin and demonstrates the breadth of clinical cancer research supported by the NCI.
To find other cancer trials open to enrollment:
- Call the National Cancer Institute’s Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
- Use the basic PDQ search form to look online for trials listed in NCI's clinical trials database. The top of the form has a Help link for tips about searching for clinical trials.
- For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call the National Cancer Institute’s Clinical Studies Support Center at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
1. New Drug for Patients with Advanced Thyroid Cancer
(Posted: 11/18/2008) - In this phase II trial, researchers are studying the effects of treatment with 17-AAG, an antitumor antibiotic drug that targets a protein called HSP90, in patients with advanced medullary or differentiated thyroid cancer.
2. Comparing Surgical Treatment for Small NSCLC Tumors
(Posted: 11/04/2008) - In this randomized phase III trial, patients with stage 1A non-small cell lung cancer tumors measuring 2 centimeters or less and located in the outer third of the lung are randomly assigned to sublobar resection (either wedge resection or segmentectomy) or lobectomy.
3. Comparison of Chemotherapy Combinations for Colon Cancer
(Posted: 10/05/2004, Updated: 10/28/2008) - Researchers with this study are comparing combination chemotherapy and biological therapy regimens for stage III colon cancer following surgery.
4. Preventing Respiratory Infections in Patients with CLL
(Posted: 10/21/2008) - This Featured Clinical Trial is a randomized, double-blind, placebo-controlled study to test the ability of CVT-E002 (COLD-fx) to reduce acute respiratory infections and the need for antibiotic treatment during the peak respiratory illness season (January through March) in people with chronic lymphocytic leukemia.
5. Using Circulating Tumor Cells to Guide Treatment
(Posted: 10/07/2008) - In this trial, women with metastatic breast cancer who are scheduled to undergo chemotherapy will be tested to determine their blood level of circulating tumor cells (CTCs) before treatment. Those with elevated CTCs will be tested again after the first round of chemotherapy and either stay on their current chemotherapy regimen or be assigned to a new regimen if their CTCs are still elevated.
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