The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information

Added text to state that NHL in infants is rare and retrospective review demonstrated an inferior outcome for infants when compared to older patients with NHL (cited Mann et al. as reference 4). [Level of evidence: 3iiA].

Cellular Classification

Added text about a case report of a 14 year old boy with refractory primary central nervous system lymphoma, with an excellent result of repeated intravenous and intraventricular doses of rituxumab (cited Akyuz et al. as reference 41).

Disseminated Childhood B-cell Non-Hodgkin Lymphoma

Added text about data that suggests that secondary cytogenetic abnormalities, other than c-myc rearrangement, are associated with an inferior outcome. The prognostic role of minimal residual disease in the treatment of Burkitt leukemia remains unclear with results from a single study suggest inferior outcome for patients with detectable MRD. Testicular disease at diagnosis does not seem to confer poor prognosis (cited Onciu et al., Mussolin et al., and Dalle et al. as references 7, 8 and 9, respectively).

Back to Top

< Previous Section  |  Next Section >